Search results for " corticosteroidi"

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Ocular Drug Delivery Systems per la veicolazione di molecole bioattive al segmento posteriore dell'occhio

Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoBiopolimeri Micelle Polimeriche Scaffold Fibrillari Inserti oftalmici Colliri Corticosteroidi Anti-VEGF Transcorneal Penetration Enhancers Mucoadesione Human Corneal Epithelial Cells Human Retinal Pigment Epithelial Cells Ex Vivo Cornee Bovine Elettrospinning Reattore al Plasma

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OCULAR DRUG CARRIERS NANOSTRUTTURATI PER IL TRATTAMENTO DELLE PATOLOGIE DEGENERATIVE DELLA RETINA

Il lavoro di ricerca svolto è stato incentrato sulla preparazione e caratterizzazione di diversi ocular drug carriers nanostrutturati in grado di veicolare molecole bioattive per il trattamento delle retinopatie. Tali sistemi sono stati preparati utilizzando differenti derivati polimerici, ottenuti a partire dall’acido ialuronico (HA) a differente peso molecolare (10-240 kDa). Allo scopo di ottenere micelle polimeriche per la veicolazione di corticosteroidi, sono stati sintetizzati diversi derivati polimerici partendo dall’HA con MW di 10 kDa. Il derivato siglato HAC16b ha mostrato delle caratteristiche vantaggiose, in termini di dimensione, proprietà mucoadesive, valori di drug loading e p…

acido ialuronico micelle polimeriche nanoparticelle polimeriche corticosteroidi imatinib patologie retinicheSettore CHIM/09 - Farmaceutico Tecnologico Applicativo

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